Annotation Detail

Information
Associated Genes
RAF1
Associated Variants
RAF1 EXPRESSION
Source Database
MMMP
Description
Sorafenib: BRAF, CRAF, VEGFR and PDGFR inhibitor. CRAF seems to act through Bcl-2
MMMP State
expressed
MMMP Molecule
CRAF
MMMP Molecule Alias
C-Raf
MMMP Relationship
sensitivity to
MMMP Drug
Sorafenib
MMMP Drug Alias
Nexavar (R)
MMMP Model
4
MMMP Reference
Smalley KS, Oncogene 2009, 28:85-94
Drugs
Drug NameSensitivitySupported
SorafenibSensitivitytrue