Annotation Detail
Information
- Associated Genes
- CTLA4
- Associated Variants
- CTLA4 UNDEREXPRESSION
- Source Database
- MMMP
- Description
- Tumor vaccines expressing Flt3 ligand synergize with CTLA-4 blockade to reject preimplanted melanoma
- MMMP Molecule
- CTLA4
- MMMP State
- inhibited by
- MMMP Modifier
- CTLA4 antibody (antagonist)
- MMMP Relationship
- sensitivity to
- MMMP Drug
- Vaccine (Flt3 expressing melanoma)
- MMMP Model
- 2
- MMMP Reference
- Curran MA, Cancer Res 2009, 69:7747-55
- MMMP DNA/mRNA/Protein
- protein
Drugs
| Drug Name | Sensitivity | Supported |
|---|---|---|
| Vaccine (Flt3 expressing melanoma) | Sensitivity | true |