Annotation Detail
Information
- Associated Genes
- KDR
- Associated Variants
- KDR UNDEREXPRESSION
- Source Database
- MMMP
- Description
- A combination of metronomic vinblastine therapy and a vascular endothelial growth factor receptor 2-blocking antibody (DC101) results in significant control of metastatic disease and a significant improvement in median survival
- MMMP State
- inhibited by
- MMMP Molecule
- VEGFR2
- MMMP Molecule Alias
- VEGF receptor 2
- MMMP Modifier
- VEGFR2 antibody (antagonist)
- MMMP Modifier Alias
- DC101
- MMMP Relationship
- sensitivity to
- MMMP Drug
- Vinblastine
- MMMP Model
- 4
- MMMP Reference
- Cruz-Munoz W, Clin Cancer Res 2009, 15:4867-74
- MMMP DNA/mRNA/Protein
- protein
Drugs
| Drug Name | Sensitivity | Supported |
|---|---|---|
| Vinblastine | Sensitivity | true |