Annotation Detail
Information
- Associated Genes
- DHFR
- Associated Variants
- DHFR UNDEREXPRESSION
- Source Database
- MMMP
- Description
- The authors screened 2,000 compounds from the Spectrum Library in human melanoma cell lines to identify compounds that enhanced the cytotoxic effect of temozolomide
- MMMP State
- inhibited by
- MMMP Molecule
- DHFR
- MMMP Molecule Alias
- Dihydrofolate reductase
- MMMP Modifier
- Pyrimethamine
- MMMP Relationship
- sensitivity to
- MMMP Drug
- Temozolomide
- MMMP Drug Alias
- TMZ
- MMMP Model
- 3
- MMMP Reference
- Chen M, Mol Cancer Res 2009, 7:703-12
- MMMP DNA/mRNA/Protein
- protein
Drugs
| Drug Name | Sensitivity | Supported |
|---|---|---|
| Temozolomide | Sensitivity | true |