Annotation Detail
Information
- Associated Genes
- NQO1
- Associated Variants
- NQO1 UNDEREXPRESSION
- Source Database
- MMMP
- Description
- Genetic (siRNA) or pharmacological (dicoumarol) antagonism of NQO1 strongly sensitized G361 cells to DCPIP apoptogenic activity
- MMMP State
- inhibited by
- MMMP Molecule
- NQO1
- MMMP Molecule Alias
- NADPH quinone oxidoreductase
- MMMP Modifier
- Dicoumarol
- MMMP Relationship
- sensitivity to
- MMMP Drug
- DCPIP
- MMMP Drug Alias
- MMMP Model
- 3
- MMMP Reference
- Cabello CM, Biochem Pharmacol 2009, 78:344-54
- MMMP DNA/mRNA/Protein
- protein
Drugs
| Drug Name | Sensitivity | Supported |
|---|---|---|
| DCPIP | Sensitivity | true |