Annotation Detail
Information
- Associated Genes
- MAP2K7
- Associated Variants
- MAP2K7 UNDEREXPRESSION
- Source Database
- MMMP
- Description
- PD98059: selective MEK1-2 inhibitor. Administration of the PD98059-nanoparticles in melanoma-bearing mice inhibits tumor growth and enhances the antitumor efficacy of cisplatin chemotherapy
- MMMP State
- inhibited by
- MMMP Molecule
- MEK
- MMMP Modifier
- PD98059
- MMMP Modifier Alias
- MEK inhibitor
- MMMP Relationship
- sensitivity to
- MMMP Drug
- Cisplatin
- MMMP Drug Alias
- CDDP
- MMMP Model
- 2
- MMMP Reference
- Basu S, Proc Natl Acad Sci USA 2009, 106:7957-61
- MMMP DNA/mRNA/Protein
- protein
Drugs
| Drug Name | Sensitivity | Supported |
|---|---|---|
| Cisplatin | Sensitivity | true |