Annotation Detail
Information
- Associated Genes
- MAPK8
- Associated Variants
- MAPK8 UNDEREXPRESSION
- Source Database
- MMMP
- Description
- Suppression of JNK activation with the specific inhibitor SP600125 prevented FNQ-mediated cell death
- MMMP State
- inhibited by
- MMMP Molecule
- JNK
- MMMP Modifier
- SP600125
- MMMP Modifier Alias
- JNK inhibitor
- MMMP Relationship
- resistance to
- MMMP Drug
- 2-acetyl furanonaphthoquinone
- MMMP Drug Alias
- FNQ
- MMMP Model
- 3
- MMMP Reference
- Rieber M, Cancer Biol Ther 2008, 7:1206-11
- MMMP DNA/mRNA/Protein
- protein
Drugs
| Drug Name | Sensitivity | Supported |
|---|---|---|
| 2-acetyl furanonaphthoquinone | Resitance or Non-Reponse | true |