Annotation Detail
Information
- Associated Genes
- GOLPH3
- Associated Variants
- GOLPH3 EXPRESSION
- Source Database
- MMMP
- Description
- GOLPH3 acts as an oncogene as it promotes tumorigenesis in a xenograft melanoma model. Its inhibition decreases anchorage-independent growth in vitro in melanoma cell lines overexpressing GOLPH3 (but not in those not expressing it)
- MMMP State
- expressed
- MMMP Molecule
- GOLPH3
- MMMP Relationship
- sensitivity to
- MMMP Drug
- GOLPH3 siRNA
- MMMP Model
- 4
- MMMP Reference
- Scott KL, Nature 2009, 459:1085-90
- MMMP DNA/mRNA/Protein
- mRNA
Drugs
| Drug Name | Sensitivity | Supported |
|---|---|---|
| GOLPH3 siRNA | Sensitivity | true |