Annotation Detail
Information
- Associated Genes
- PRRT2
- Associated Variants
- PRRT2 EXPRESSION
- Source Database
- MMMP
- Description
- Two diterpene esters, prototypic PKC-activating drug TPA and the novel PKC-activating drug PEP008, induce growth arrest with characteristics of senescence in solid tumor cell lines derived from a variety of tissue types including melanoma
- MMMP State
- expressed
- MMMP Molecule
- PKC
- MMMP Molecule Alias
- Protein kinase C
- MMMP Relationship
- sensitivity to
- MMMP Drug
- TPA
- MMMP Drug Alias
- Tetradecanoyl phorbol acetate
- MMMP Model
- 3
- MMMP Reference
- Mason SA, Invest New Drugs 2010, 28:575-86
- MMMP DNA/mRNA/Protein
- protein
Drugs
| Drug Name | Sensitivity | Supported |
|---|---|---|
| TPA | Sensitivity | true |