Annotation Detail
Information
- Associated Genes
- CTLA4
- Associated Variants
- CTLA4 UNKNOWN
- Source Database
- MMMP
- Description
- Phase III RCT. Setting: metastatic, all patients were HLA-A0201 positive. Ipilimumab, with or without a gp100 peptide vaccine, as compared with gp100 alone, improved overall survival in patients with previously treated metastatic melanoma
- MMMP State
- uncharacterized
- MMMP Molecule
- CTLA4
- MMMP Relationship
- sensitivity to
- MMMP Drug
- Ipilimumab
- MMMP Drug Alias
- CTLA4 antibody (antagonist)
- MMMP Model
- 6
- MMMP Reference
- Hodi FS, N Engl J Med 2010, 363:711-23
Drugs
| Drug Name | Sensitivity | Supported |
|---|---|---|
| Ipilimumab | Sensitivity | true |