Annotation Detail

Information
Associated Genes
MSH2
Associated Variants
MSH2 rs2303428
MSH2 c.2006-6T>C ( ENST00000543555.6, ENST00000233146.7, ENST00000406134.5, ENST00000645506.1, ENST00000713854.1, ENST00000713919.1 )
MSH2 rs2303428
Source Database
MMMP
Description
The genetic variant rs2303428 (MSH2) might serve as a predictive marker for chemotherapy response (test for trend P-value = 0.04)
MMMP State
polymorphism rs2303428
MMMP Molecule
MSH2
MMMP Relationship
sensitivity to
MMMP Drug
Dacarbazine
MMMP Drug Alias
DTIC
MMMP Model
5
MMMP Reference
Boeckmann L, Pharmacogenet Genomics 2009, 19:760-9
MMMP DNA/mRNA/Protein
DNA
Drugs
Drug NameSensitivitySupported
DacarbazineSensitivitytrue