Annotation Detail

Information
Associated Genes
AKT2
Associated Variants
AKT2 EXPRESSION
Source Database
MMMP
Description
Metabotropic glutamate receptor 1 (Grm1) acts as an oncogene in vitro and in vivo. A reduction in tumor volume of Grm1-mouse-melanocytic-allografts was detected in the presence of small interfering AKT2 RNA (siAKT2).
MMMP State
expressed
MMMP Molecule
AKT2
MMMP Relationship
sensitivity to
MMMP Drug
AKT2 siRNA
MMMP Model
2
MMMP Reference
Shin SS, Pigment Cell Melanoma Res 2010, 23:103-11
MMMP DNA/mRNA/Protein
mRNA
Drugs
Drug NameSensitivitySupported
AKT2 siRNASensitivitytrue