Annotation Detail
Information
- Associated Genes
- CD226
- Associated Variants
- CD226 UNDEREXPRESSION
- Source Database
- MMMP
- Description
- NK cells require DNAM-1 for natural or cytokine (IL-2, IL-12, or IL-21) suppression of tumor metastases
- MMMP State
- downregulated by
- MMMP Molecule
- DNAM1
- MMMP Molecule Alias
- CD226
- MMMP Modifier
- DNAM-1 knockout
- MMMP Relationship
- resistance to
- MMMP Drug
- IL-2
- MMMP Drug Alias
- Interleukin-2
- MMMP Model
- 2
- MMMP Reference
- Chan CJ, J Immunol 2010, 184:902-11
- MMMP DNA/mRNA/Protein
- mRNA
Drugs
| Drug Name | Sensitivity | Supported |
|---|---|---|
| IL-2 | Resitance or Non-Reponse | true |