Annotation Detail
Information
- Associated Genes
- EGFR
- Associated Variants
- EGFR EXPRESSION
- Source Database
- MMMP
- Description
- Erlotinib: small molecule inhibitor of EGFR. While in vitro no influence on tumor cell proliferation was seen with erlotinib or bevacizumab monotherapy, a decreased invasive potential on erlotinib treatment in a three-dimensional Matrigel assay was observed. EGFR was expressed in all cell lines tested
- MMMP State
- expressed
- MMMP Molecule
- EGFR
- MMMP Molecule Alias
- ERBB1
- MMMP Relationship
- sensitivity to
- MMMP Drug
- Erlotinib
- MMMP Drug Alias
- Tarceva (R)
- MMMP Model
- 3
- MMMP Reference
- Schicher N, Clin Cancer Res 2009, 15:3495-502
Drugs
| Drug Name | Sensitivity | Supported |
|---|---|---|
| Erlotinib | Sensitivity | true |