Annotation Detail
Information
- Associated Genes
- MAP2K7
- Associated Variants
- MAP2K7 EXPRESSION
- Source Database
- MMMP
- Description
- AZD6244: MEK inhibitor. In two-dimensional cell culture, AZD6244 was cytostatic and reduced the growth of melanoma cells in a concentration-dependent fashion through the induction of G(1)-phase cell cycle arrest
- MMMP State
- expressed
- MMMP Molecule
- MEK
- MMMP Relationship
- sensitivity to
- MMMP Drug
- AZD6244
- MMMP Model
- 3
- MMMP Reference
- Haass NK, Clin Cancer Res 2008, 14:230-9
Drugs
| Drug Name | Sensitivity | Supported |
|---|---|---|
| AZD6244 | Sensitivity | true |