Annotation Detail
Information
- Associated Genes
- TP53
- Associated Variants
- TP53 WILD_TYPE
- Source Database
- MMMP
- Description
- Melanoma lines expressing p53 wild-type were more resistant to TMZ and fotemustine than p53 mutant melanoma lines, which is in marked contrast to previous data reported for glioma cells treated with TMZ
- MMMP State
- wild type (vs mutated)
- MMMP Molecule
- p53
- MMMP Molecule Alias
- TP53
- MMMP Relationship
- resistance to
- MMMP Drug
- Fotemustine
- MMMP Model
- 3
- MMMP Reference
- Naumann SC, Br J Cancer 2009, 100:322-33
- MMMP DNA/mRNA/Protein
- DNA
Drugs
| Drug Name | Sensitivity | Supported |
|---|---|---|
| Fotemustine | Resitance or Non-Reponse | true |