Annotation Detail
Information
- Associated Genes
- KIT
- Associated Variants
- KIT UNKNOWN
- Source Database
- MMMP
- Description
- Mucosal melanoma; no active control trial (historical comparison). Sorafenib: BRAF CRAF VEGFR PDGFR inhibitor
- MMMP State
- mut V560A (exon 11)
- MMMP Molecule
- KIT
- MMMP Molecule Alias
- c-KIT
- MMMP Relationship
- sensitivity to
- MMMP Drug
- Sorafenib
- MMMP Drug Alias
- Nexavar (R)
- MMMP Model
- 5
- MMMP Reference
- Quintas-Cardama A, Nat Clin Pract Oncol 2008, 5:737-40
- MMMP DNA/mRNA/Protein
- DNA
Drugs
| Drug Name | Sensitivity | Supported |
|---|---|---|
| Sorafenib | Sensitivity | true |