Annotation Detail

Information
Associated Genes
POLB
Associated Variants
POLB EXPRESSION
Source Database
MMMP
Description
PARP1, POLB, APEX1, LIG1 and MPG showed no correlation with sensitivity to TMZ, suggesting that BER does not significantly contribute to TMZ resistance in melanoma
MMMP State
expressed
MMMP Molecule
POLB
MMMP Molecule Alias
DNA polymerase beta
MMMP Relationship
no relationship with
MMMP Drug
Temozolomide
MMMP Drug Alias
TMZ
MMMP Model
3
MMMP Reference
Augustine CK, Clin Cancer Res 2009, 15:502-10
Drugs
Drug NameSensitivitySupported
TemozolomideResitance or Non-Reponsetrue