Annotation Detail
Information
- Associated Genes
- PARP1
- Associated Variants
- PARP1 EXPRESSION
- Source Database
- MMMP
- Description
- PARP1, POLB, APEX1, LIG1 and MPG showed no correlation with sensitivity to TMZ, suggesting that BER does not significantly contribute to TMZ resistance in melanoma
- MMMP State
- expressed
- MMMP Molecule
- PARP-1
- MMMP Molecule Alias
- Poly ADP-ribose polymerase 1
- MMMP Relationship
- no relationship with
- MMMP Drug
- Temozolomide
- MMMP Drug Alias
- TMZ
- MMMP Model
- 3
- MMMP Reference
- Augustine CK, Clin Cancer Res 2009, 15:502-10
Drugs
| Drug Name | Sensitivity | Supported |
|---|---|---|
| Temozolomide | Resitance or Non-Reponse | true |