Annotation Detail
Information
- Associated Genes
- ABCB1
- Associated Variants
- ABCB1 EXPRESSION
- Source Database
- MMMP
- Description
- RNA interference experiments further demonstrated ABCB1 (Pgp) involvement in migration and invasion of resistant melanoma cells, likely by cooperating with CD44 through the activation of ERK1/2 and p38 mitogen-activated protein kinase (MAPK) proteins
- MMMP State
- expressed
- MMMP Molecule
- ABCB1
- MMMP Molecule Alias
- MDR1, P-gp
- MMMP Relationship
- sensitivity to
- MMMP Drug
- ABCB1 siRNA
- MMMP Model
- 3
- MMMP Reference
- Colone M, J Invest Dermatol 2008, 128:957-71
Drugs
| Drug Name | Sensitivity | Supported |
|---|---|---|
| ABCB1 siRNA | Sensitivity | true |