Annotation Detail
Information
- Associated Genes
- TP53
- Associated Variants
- TP53 WILD_TYPE
- Source Database
- MMMP
- Description
- Melanoma cells with wild type p53 had much reduced viability in the presence of TMZ compared to melanoma cells with mutated p53
- MMMP State
- wild type (vs mutated)
- MMMP Molecule
- p53
- MMMP Molecule Alias
- TP53
- MMMP Relationship
- sensitivity to
- MMMP Drug
- Temozolomide
- MMMP Drug Alias
- TMZ
- MMMP Model
- 3
- MMMP Reference
- Mhaidat NM, Br J Cancer 2007, 97:1225-33
- MMMP DNA/mRNA/Protein
- DNA
Drugs
| Drug Name | Sensitivity | Supported |
|---|---|---|
| Temozolomide | Sensitivity | true |