Annotation Detail
Information
- Associated Genes
- CTLA4
- Associated Variants
- CTLA4 UNKNOWN
- Source Database
- MMMP
- Description
- In this phase II trial (metastatic setting), anti-CTLA4 antibody tremelimumab showed an objective response rate of 6.6%, with all responses being durable > or =170 days since enrollment
- MMMP State
- uncharacterized
- MMMP Molecule
- CTLA4
- MMMP Relationship
- no relationship with
- MMMP Drug
- Tremelimumab
- MMMP Drug Alias
- CTLA4 antibody (antagonist) CP-675,206
- MMMP Model
- 5
- MMMP Reference
- Kirkwood JM, Clin Cancer Res 2010, 16:1042-8
Drugs
Drug Name | Sensitivity | Supported |
---|---|---|
Tremelimumab | Resitance or Non-Reponse | true |