Annotation Detail
Information
- Associated Genes
- ROS1
- Associated Variants
- ROS1 EXPRESSION
- Source Database
- MMMP
- Description
- The induction of oxidative stress by elesclomol exploits this unique characteristic of cancer cells by increasing ROS levels beyond a threshold that triggers cell death
- MMMP State
- expressed
- MMMP Molecule
- ROS
- MMMP Molecule Alias
- Reactive oxygen species
- MMMP Relationship
- sensitivity to
- MMMP Drug
- Elesclomol
- MMMP Model
- 3
- MMMP Reference
- Kirshner JR, Mol Cancer Ther 2008, 7:2319-27
Drugs
| Drug Name | Sensitivity | Supported |
|---|---|---|
| Elesclomol | Sensitivity | true |