Annotation Detail
Information
- Associated Genes
- SRC
- Associated Variants
- SRC EXPRESSION
- Source Database
- MMMP
- Description
- Dasatinib inhibited growth of three of the five melanoma cell lines. Dasatinib inhibition of proliferation was associated with reduced phosphorylation of Src kinase, while decreased phosphorylation of FAK was implicated in dasatinib-mediated inhibition of migration and invasion in melanoma cells
- MMMP State
- expressed
- MMMP Molecule
- SRC
- MMMP Molecule Alias
- c-Src
- MMMP Modifier Alias
- MMMP Relationship
- sensitivity to
- MMMP Drug
- Dasatinib
- MMMP Model
- 3
- MMMP Reference
- Eustace AJ, J Transl Med 2008, 6:53
Drugs
| Drug Name | Sensitivity | Supported |
|---|---|---|
| Dasatinib | Sensitivity | true |