Annotation Detail
Information
- Associated Genes
- ERBB4
- Associated Variants
- ERBB4 E452K
- Source Database
- MMMP
- Description
- Melanoma cells expressing mutationally activated ERBB4 had reduced cell growth after treatment with the ERBB inhibitor lapatinib
- MMMP State
- mut E452K
- MMMP Molecule
- ERBB4
- MMMP Relationship
- sensitivity to
- MMMP Drug
- Lapatinib
- MMMP Model
- 3
- MMMP Reference
- Prickett TD, Nat Genet 2009, 41:1127-32
- MMMP DNA/mRNA/Protein
- DNA
Drugs
| Drug Name | Sensitivity | Supported |
|---|---|---|
| Lapatinib | Sensitivity | true |