Annotation Detail

Information
Associated Genes
Associated Variants
NM_000041.4(APOE):c.[388=;526=] AND APOE3 ISOFORM
NM_000041.4(APOE):c.[388=;526=] AND APOE3 ISOFORM
Source Database
GWAS Catalog
Description
Human longevity: 25 genetic loci associated in 389,166 UK biobank participants.
GWAS Strongest risk allele
rs429358-T
GWAS Catalog disease or trait
Parental longevity (combined parental attained age, Martingale residuals)
GWAS Catalog p-Value
1E-74
GWAS Odds ratio OR beta coefficient
0.0566
GWAS 95% confidence interval
[0.051-0.063] unit decrease
GWAS parent term
Other measurement
URL
http://www.ebi.ac.uk/efo/EFO_0007796
Drugs