Annotation Detail

Information
Associated Genes
Associated Variants
NM_000771.3(CYP2C9):c.[430C=;1075A=] AND Warfarin response
NM_000771.3(CYP2C9):c.[430C=;1075A=] AND Warfarin response
Source Database
GWAS Catalog
Description
A genome-wide association study confirms VKORC1, CYP2C9, and CYP4F2 as principal genetic determinants of warfarin dose.
GWAS Catalog disease or trait
Warfarin maintenance dose
GWAS Catalog p-Value
3E-79
GWAS Odds ratio OR beta coefficient
1.11
GWAS 95% confidence interval
[1.00-1.22] mg/week decrease
GWAS parent term
Response to drug
URL
http://purl.obolibrary.org/obo/GO_0061476
Drugs