Annotation Detail

Information
Associated Genes
Associated Variants
NM_000041.4(APOE):c.[388=;526=] AND APOE3 ISOFORM
NM_000041.4(APOE):c.[388=;526=] AND APOE3 ISOFORM
Source Database
GWAS Catalog
Description
Population-based genome-wide association study of cognitive decline in older adults free of dementia: identification of a novel locus for the attention domain.
GWAS Strongest risk allele
rs429358-C
GWAS Catalog disease or trait
Age-related cognitive decline (memory) (slope of z-scores)
GWAS Catalog p-Value
7E-6
GWAS Odds ratio OR beta coefficient
0.29
GWAS 95% confidence interval
unit decrease
GWAS parent term
Other measurement
URL
http://www.ebi.ac.uk/efo/EFO_0007710
Drugs