Annotation Detail

Information
Associated Genes
Associated Variants
NM_000777.5(CYP3A5):c.219-237A>G AND Hypertension, salt-sensitive essential, susceptibility to
NM_000777.5(CYP3A5):c.219-237= AND not provided
Source Database
GWAS Catalog
Description
Genetic Variants Associated with Immunosuppressant Pharmacokinetics and Adverse Effects in the DeKAF Genomics Genome Wide Association Studies.
GWAS Catalog disease or trait
Tacrolimus trough concentration in kidney transplant patients
GWAS Catalog p-Value
5E-35
GWAS Odds ratio OR beta coefficient
0.4488
GWAS 95% confidence interval
[0.38-0.52] unit increase
GWAS parent term
Other trait
URL
http://www.ebi.ac.uk/efo/EFO_0010134
GWAS parent term
Other measurement
URL
http://www.ebi.ac.uk/efo/EFO_0005199
URL
http://www.ebi.ac.uk/efo/EFO_0008458
Drugs