Annotation Detail

Information
Associated Genes
Associated Variants
NM_000777.5(CYP3A5):c.219-237A>G AND Hypertension, salt-sensitive essential, susceptibility to
NM_000777.5(CYP3A5):c.219-237= AND not provided
Source Database
GWAS Catalog
Description
Genetic studies of urinary metabolites illuminate mechanisms of detoxification and excretion in humans.
GWAS Strongest risk allele
rs776746-T
GWAS Catalog disease or trait
Urinary metabolite modules (eigenmetabolites) in chronic kidney disease
GWAS Catalog p-Value
3E-18
GWAS Odds ratio OR beta coefficient
0.015
GWAS 95% confidence interval
[0.011-0.019] unit decrease
GWAS parent term
Other disease
URL
http://www.ebi.ac.uk/efo/EFO_0003884
GWAS parent term
Other measurement
URL
http://www.ebi.ac.uk/efo/EFO_0005116
Drugs