Annotation Detail

Information
Associated Genes
Associated Variants
NM_000041.4(APOE):c.[388=;526=] AND APOE3 ISOFORM
NM_000041.4(APOE):c.[388=;526=] AND APOE3 ISOFORM
Source Database
GWAS Catalog
Description
GWAS and colocalization analyses implicate carotid intima-media thickness and carotid plaque loci in cardiovascular outcomes.
GWAS Strongest risk allele
rs7412-T
GWAS Catalog disease or trait
Carotid intima media thickness
GWAS Catalog p-Value
1E-14
GWAS Odds ratio OR beta coefficient
0.0119
GWAS 95% confidence interval
[0.009-0.0148] unit decrease
GWAS parent term
Other measurement
URL
http://www.ebi.ac.uk/efo/EFO_0007117
GWAS parent term
Cardiovascular measurement
URL
http://www.ebi.ac.uk/efo/EFO_0004860
GWAS parent term
Cardiovascular disease
URL
http://www.ebi.ac.uk/efo/EFO_0003914
Drugs