Annotation Detail

Information
Associated Genes
Associated Variants
NM_000041.4(APOE):c.[388=;526=] AND APOE3 ISOFORM
NM_000041.4(APOE):c.[388=;526=] AND APOE3 ISOFORM
Source Database
GWAS Catalog
Description
Genome-wide association analysis of dementia and its clinical endophenotypes reveal novel loci associated with Alzheimer's disease and three causality networks: The GR@ACE project.
GWAS Strongest risk allele
rs429358-C
GWAS Catalog disease or trait
Alzheimer’s disease (clinical subgroup AD+++)
GWAS Catalog p-Value
1E-75
GWAS Odds ratio OR beta coefficient
2.92
GWAS 95% confidence interval
[3.27-2.6]
GWAS parent term
Neurological disorder
URL
http://www.ebi.ac.uk/efo/EFO_0000249
Drugs