Annotation Detail
Information
- Associated Genes
- Associated Variants
-
NM_000041.4(APOE):c.[388=;526=] AND APOE3 ISOFORM
NM_000041.4(APOE):c.[388=;526=] AND APOE3 ISOFORM - Source Database
- GWAS Catalog
- Description
- SUCLG2 identified as both a determinator of CSF Aβ1-42 levels and an attenuator of cognitive decline in Alzheimer's disease.
- GWAS Catalog disease or trait
- Cerebrospinal AB1-42 levels in Alzheimer's disease dementia
- GWAS Catalog p-Value
- 4E-17
- GWAS Odds ratio OR beta coefficient
- 0.4
- GWAS 95% confidence interval
- [0.30-0.50] unit decrease
- GWAS parent term
- Neurological disorder
- URL
- http://www.ebi.ac.uk/efo/EFO_0000249
- GWAS parent term
- Other measurement
- URL
- http://www.ebi.ac.uk/efo/EFO_0004670
Drugs