Annotation Detail
Information
- Associated Genes
- PARP1
- Associated Variants
-
PARP1 p.Val762Ala (p.V762A)
(
ENST00000366794.10,
ENST00000677203.1 )
PARP1 p.Val762Ala (p.V762A) ( ENST00000366794.10, ENST00000677203.1 ) - Associated Disease
- Malignant neoplasm of prostate
- Source Database
- DisGeNET
- Description
- Genetic analyses of the PARP-1 gene have demonstrated alterations in neoplasms, and a mutation affecting the conserved amino acid E251 in germ cell tumors, as well as an association of a single-nucleotide polymorphism V762A with risk of prostate cancer.
- Pubmed
- 15868402
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.00969596252477022
- Year of publication
- 2005
Drugs