Annotation Detail

Information
Associated Genes
ALPP
Associated Variants
ALPP MUTATION
ALPP MUTATION
Associated Disease
renal cell carcinoma
Source Database
DisGeNET
Description
This is the first study that suggests deactivation of ERK1/2 by stimulation of ALP in renal cancer cell lines which can be used as a therapeutic target of RCC.
Pubmed
25241253
Section of the abstract supporting the evidence
ALL_TEXT_3/3
Number of the section of the abstract supporting the evidence
3
Number of the sentence supporting the evidence
7
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.000542883744160607
Drugs