Annotation Detail

Information
Associated Genes
TERF2
Associated Variants
TERF2 MUTATION
TERF2 MUTATION
Associated Disease
renal cell carcinoma
Source Database
DisGeNET
Description
Over-expression of telomere binding factors (TRF1 & TRF2) in renal cell carcinoma and their inhibition by using SiRNA induce apoptosis, reduce cell proliferation and migration invitro.
Pubmed
25730259
Section of the abstract supporting the evidence
TITLE
Number of the section of the abstract supporting the evidence
0
Number of the sentence supporting the evidence
0
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.000271441872080303
Drugs