Annotation Detail

Information
Associated Genes
FGFR4
Associated Variants
FGFR4 MUTATION
FGFR4 MUTATION
Associated Disease
Malignant tumor of colon
Source Database
DisGeNET
Description
The administration of FGF-1/-3-neutralizing antibodies or the treatment of cells with FGFR4 siRNA or the FGFR4 inhibitor PD173074 markedly suppressed colon cancer cell proliferation and neovascularization.
Pubmed
26183471
Section of the abstract supporting the evidence
ALL_TEXT_3/3
Number of the section of the abstract supporting the evidence
3
Number of the sentence supporting the evidence
7
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.00162865123248182
Drugs