Annotation Detail

Information
Associated Genes
MLH1
Associated Variants
MLH1 MUTATION
MLH1 MUTATION
Associated Disease
Malignant tumor of colon
Source Database
DisGeNET
Description
Among all the 32 families with mutations, families with hMSH2 mutation had a higher ratio of synchronous and metachronous colon cancers than families with hMLH1 mutation (33 vs. 6%, P=0.04).
Pubmed
25216868
Section of the abstract supporting the evidence
ALL_TEXT_3/3
Number of the section of the abstract supporting the evidence
3
Number of the sentence supporting the evidence
10
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.0236154428709864
Drugs