Annotation Detail

Information
Associated Genes
SLC40A1
Associated Variants
HAMP c.-84-498A>G ( ENST00000598398.5 )
FTL p.Leu55= (p.L55=) ( ENST00000331825.11 )
NC_000020.11:g.6786464A>G
SLC40A1 c.44-24G>C ( ENST00000261024.7 )
HAMP c.-84-498A>G ( ENST00000598398.5 )
FTL p.Leu55= (p.L55=) ( ENST00000331825.11 )
NC_000020.11:g.6786464A>G
SLC40A1 c.44-24G>C ( ENST00000261024.7 )
Associated Disease
Hereditary hemochromatosis
Source Database
DisGeNET
Description
Our results make it likely the role of rs10421768, rs235756, rs2230267 and rs1439816 polymorphisms, respectively in HAMP, BMP2, FTL and SLC40A1 genes in HH expressivity.
Pubmed
25976471
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.00298586059288334
Year of publication
2015
Drugs