Annotation Detail

Information
Associated Genes
SLC6A4
Associated Variants
SLC6A4 c.*463T>G ( ENST00000650711.1, ENST00000261707.7, ENST00000401766.6 )
ITGB3 c.*1016T>A ( ENST00000559488.7 )
SLC6A4 c.*463T>G ( ENST00000261707.7, ENST00000401766.6, ENST00000650711.1 )
ITGB3 c.*1016T>A ( ENST00000559488.7 )
Associated Disease
autistic disorder
Source Database
DisGeNET
Description
Analyzing four markers in SLC6A4 and four markers in ITGB3 in 117 white family triads with autism and using sex of the proband as a PC, we found significant interaction between two markers--rs1042173 in SLC6A4 and rs3809865 in ITGB3.
Pubmed
17999363
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.26754300906276
Year of publication
2007
Drugs