Annotation Detail

Information
Associated Genes
SLC6A4
Associated Variants
SLC6A4 c.*463T>G ( ENST00000650711.1, ENST00000261707.7, ENST00000401766.6 )
SLC6A4 c.*463T>G ( ENST00000261707.7, ENST00000401766.6, ENST00000650711.1 )
Associated Disease
Headache
Source Database
DisGeNET
Description
Although a minor contribution of SLC6A4 variants in the genetic liability of MOH cannot be excluded, haplotype-based analysis of STin2 VNTR and rs1042173T>G polymorphisms allowed to identify a subgroup of MOH patients with a higher number of monthly headache and, possibly, with a more severe disease.
Pubmed
21585624
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.00135720936040152
Year of publication
2012
Drugs