Annotation Detail

Information
Associated Genes
ARID1A
Associated Variants
ARID1A MUTATION
ARID1A MUTATION
Associated Disease
Burkitt lymphoma
Source Database
DisGeNET
Description
Here, we discuss the function of histone acetyltransferases (CREBBP, EP300), histone methyltransferases (KDM2C/D, EZH2) and regulators of higher order chromatin structure (HIST1H1C/D/E, ARID1A and SMARCA4) that have been reported to be mutated in ⩾5% of DLBCL, FL or BL.
Pubmed
26473533
Section of the abstract supporting the evidence
ALL_TEXT_3/3
Number of the section of the abstract supporting the evidence
3
Number of the sentence supporting the evidence
5
Original source reporting the Gene Disease association
BeFree,CTD_human
DisGENET score for the Gene Disease association
0.120542883744161
Drugs