Annotation Detail

Information
Associated Genes
IL1B
Associated Variants
IL1B c.*505G>C ( ENST00000263341.7 )
IL1B c.-118C>T
IL4 c.184-574G>A ( ENST00000231449.7, ENST00000350025.2, ENST00000622422.1 )
LTA c.-18G>A ( ENST00000454783.5, ENST00000418386.3 )
LTA p.Thr60Asn (p.T60N) ( ENST00000454783.5, ENST00000418386.3 )
IL1B c.*505G>C ( ENST00000263341.7 )
IL1B c.-118C>T
IL4 c.184-574G>A ( ENST00000231449.7, ENST00000350025.2, ENST00000622422.1 )
LTA c.-18G>A ( ENST00000418386.3, ENST00000454783.5 )
LTA p.Thr60Asn (p.T60N) ( ENST00000418386.3, ENST00000454783.5 )
Associated Disease
Fatigue
Source Database
DisGeNET
Description
Controlling for genomic estimates of ancestry and self-reported race/ethnicity and gender, the high fatigue pattern was associated with five single nucleotide polymorphisms (SNPs): IL1B rs1071676 and rs1143627, IL4 rs2243274, and TNFA rs1800683 and rs1041981.
Pubmed
24632226
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.00162865123248182
Year of publication
2014
Drugs