Annotation Detail

Information
Associated Genes
XRCC4
Associated Variants
XRCC4 MUTATION
XRCC4 MUTATION
Associated Disease
Malignant neoplasm of breast
Source Database
DisGeNET
Description
A recessive variant of XRCC4 predisposes to non- BRCA1/2 breast cancer in chinese women and impairs the DNA damage response via dysregulated nuclear localization.
Pubmed
25360583
Section of the abstract supporting the evidence
TITLE
Number of the section of the abstract supporting the evidence
0
Number of the sentence supporting the evidence
0
Original source reporting the Gene Disease association
BeFree,GAD
DisGENET score for the Gene Disease association
0.0169166105924152
Drugs