Annotation Detail
Information
- Associated Genes
- TNFAIP3
- Associated Variants
-
TNIP1 c.435+891G>A
(
ENST00000315050.11,
ENST00000389378.6,
ENST00000518977.5,
ENST00000520695.6,
ENST00000520931.5,
ENST00000521001.2,
ENST00000521591.6,
ENST00000522100.6,
ENST00000522226.5,
ENST00000523200.5,
ENST00000523338.5,
ENST00000524280.5,
ENST00000610535.5 )
TNIP1 c.-37+1739G>A ( ENST00000315050.11, ENST00000389378.6, ENST00000518977.5, ENST00000520695.6, ENST00000520931.5, ENST00000521001.2, ENST00000521591.6, ENST00000522100.6, ENST00000522226.5, ENST00000523338.5, ENST00000610535.5 )
TNIP1 c.435+891G>A ( ENST00000315050.11, ENST00000389378.6, ENST00000518977.5, ENST00000520695.6, ENST00000520931.5, ENST00000521001.2, ENST00000521591.6, ENST00000522100.6, ENST00000522226.5, ENST00000523200.5, ENST00000523338.5, ENST00000524280.5, ENST00000610535.5 )
TNIP1 c.-37+1739G>A ( ENST00000315050.11, ENST00000389378.6, ENST00000518977.5, ENST00000520695.6, ENST00000520931.5, ENST00000521001.2, ENST00000521591.6, ENST00000522100.6, ENST00000522226.5, ENST00000523338.5, ENST00000610535.5 ) - Associated Disease
- asthma
- Source Database
- DisGeNET
- Description
- Multiple single nucleotide polymorphisms in the TNFAIP3 interacting protein 1 (TNIP1) gene, which interacts with TNFAIP3 and inhibits the TNF-α-induced nuclear factor κB inflammation pathway, were associated with asthma: rs1422673 (P = 3.44 × 10(-7)) and rs10036748 (P = 1.41 × 10(-6), r(2) = 0.67).
- Pubmed
- 22694930
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.000542883744160607
- Year of publication
- 2012
Drugs