Annotation Detail

Information
Associated Genes
MMP1
Associated Variants
MMP1 MUTATION
MMP1 MUTATION
Associated Disease
Malignant neoplasm of breast
Source Database
DisGeNET
Description
Tyrosyl phosphorylated PAK1 also stimulates invasion of breast cancer cells in response to PRL and three-dimensional (3D) collagen IV via transcription and secretion of MMP-1 and MMP-3 in a MAPK-dependent manner.
Pubmed
25472536
Section of the abstract supporting the evidence
ALL_TEXT_3/3
Number of the section of the abstract supporting the evidence
3
Number of the sentence supporting the evidence
6
Original source reporting the Gene Disease association
BeFree,GAD
DisGENET score for the Gene Disease association
0.0234312155223425
Drugs