Annotation Detail
Information
- Associated Genes
- JAK1
- Associated Variants
-
JAK1 MUTATION
JAK1 MUTATION - Associated Disease
- Behcet Syndrome
- Source Database
- DisGeNET
- Description
- The JAK1/STAT3 signaling pathway is activated in BD, possibly through the activation of Th1/Th17-type cytokines such as IL-2, interferon (IFN-γ), IL-6, IL-17 and IL-23.
- Pubmed
- 25410656
- Section of the abstract supporting the evidence
- ALL_TEXT_3/3
- Number of the section of the abstract supporting the evidence
- 3
- Number of the sentence supporting the evidence
- 10
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.00081432561624091
Drugs