Annotation Detail
Information
- Associated Genes
- PIK3CD
- Associated Variants
-
PIK3CD MUTATION
PIK3CD MUTATION - Associated Disease
- Autoimmune Diseases
- Source Database
- DisGeNET
- Description
- Selective inhibition of PI3Kδ, γ or β has each been shown to reduce the severity of inflammation in one or more models of autoimmune disease, respiratory disease or allergic inflammation, with dual γ/δ or β/δ inhibition generally proving more effective.
- Pubmed
- 25514767
- Section of the abstract supporting the evidence
- ALL_TEXT_3/3
- Number of the section of the abstract supporting the evidence
- 3
- Number of the sentence supporting the evidence
- 11
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.000542883744160607
Drugs