Annotation Detail

Information
Associated Genes
CASP9
Associated Variants
CASP9 MUTATION
CASP9 MUTATION
Associated Disease
atherosclerosis
Source Database
DisGeNET
Description
The mRNA expression of CASP3 was found to be steadily decreasing with the progression of atherosclerosis while the expression of CASP9 showed a pattern which can be described as a bell-shaped relationship between gene mRNA expression and the type of atherosclerotic lesion, with the maximum being observed in fatty streaks.
Pubmed
25962658
Section of the abstract supporting the evidence
ALL_TEXT_3/3
Number of the section of the abstract supporting the evidence
3
Number of the sentence supporting the evidence
5
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.000271441872080303
Drugs