Annotation Detail
Information
- Associated Genes
- TSPYL2
- Associated Variants
-
KRAS p.Gln61Glu (p.Q61E)
(
ENST00000557334.6,
ENST00000256078.10,
ENST00000688940.1,
ENST00000311936.8,
ENST00000692768.1,
ENST00000685328.1,
ENST00000693229.1 )
KRAS p.Gln61Lys (p.Q61K) ( ENST00000311936.8, ENST00000693229.1, ENST00000692768.1, ENST00000557334.6, ENST00000688940.1, ENST00000256078.10, ENST00000685328.1 )
KRAS p.Gly13Val (p.G13V) ( ENST00000256078.10, ENST00000311936.8, ENST00000556131.2, ENST00000557334.6, ENST00000685328.1, ENST00000686969.1, ENST00000688940.1, ENST00000692768.1, ENST00000693229.1 )
KRAS p.Gly13Ala (p.G13A) ( ENST00000557334.6, ENST00000256078.10, ENST00000688940.1, ENST00000311936.8, ENST00000686969.1, ENST00000685328.1, ENST00000693229.1, ENST00000692768.1, ENST00000556131.2 )
KRAS p.Gly13Asp (p.G13D) ( ENST00000256078.10, ENST00000311936.8, ENST00000556131.2, ENST00000685328.1, ENST00000557334.6, ENST00000686969.1, ENST00000688940.1, ENST00000692768.1, ENST00000693229.1 )
NRAS p.Gln61Glu (p.Q61E) ( ENST00000369535.5 )
NRAS p.Gln61Lys (p.Q61K) ( ENST00000369535.5 )
NRAS p.Gly13Val (p.G13V) ( ENST00000369535.5 )
NRAS p.Gly13Ala (p.G13A) ( ENST00000369535.5 )
NRAS p.Gly13Asp (p.G13D) ( ENST00000369535.5 )
KRAS p.Gln61Glu (p.Q61E) ( ENST00000256078.10, ENST00000311936.8, ENST00000557334.6, ENST00000685328.1, ENST00000688940.1, ENST00000692768.1, ENST00000693229.1 )
KRAS p.Gln61Lys (p.Q61K) ( ENST00000693229.1, ENST00000688940.1, ENST00000692768.1, ENST00000256078.10, ENST00000311936.8, ENST00000557334.6, ENST00000685328.1 )
KRAS p.Gly13Val (p.G13V) ( ENST00000256078.10, ENST00000311936.8, ENST00000556131.2, ENST00000686969.1, ENST00000688940.1, ENST00000692768.1, ENST00000693229.1, ENST00000557334.6, ENST00000685328.1 )
KRAS p.Gly13Ala (p.G13A) ( ENST00000256078.10, ENST00000311936.8, ENST00000556131.2, ENST00000557334.6, ENST00000685328.1, ENST00000686969.1, ENST00000688940.1, ENST00000692768.1, ENST00000693229.1 )
KRAS p.Gly13Asp (p.G13D) ( ENST00000556131.2, ENST00000557334.6, ENST00000256078.10, ENST00000311936.8, ENST00000685328.1, ENST00000686969.1, ENST00000688940.1, ENST00000692768.1, ENST00000693229.1 )
NRAS p.Gln61Glu (p.Q61E) ( ENST00000369535.5 )
NRAS p.Gln61Lys (p.Q61K) ( ENST00000369535.5 )
NRAS p.Gly13Val (p.G13V) ( ENST00000369535.5 )
NRAS p.Gly13Ala (p.G13A) ( ENST00000369535.5 )
NRAS p.Gly13Asp (p.G13D) ( ENST00000369535.5 ) - Associated Disease
- Sezary syndrome
- Source Database
- DisGeNET
- Description
- One mycosis fungoides and one pleomorphic CTCL harbored a KRAS(G13D) mutation; one Sézary syndrome and one CD30(+) CTCL harbored a NRAS(Q61K) amino acid change.
- Pubmed
- 21209378
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.00081432561624091
- Year of publication
- 2011
Drugs